However, it’s very difficult to stay anabolic for long periods of time because our bodies fight us every step of the way. Thanks to thousands of years of human evolution, building muscle takes time. In fact, our bodies prefer to be in neutral state – neither too anabolic or too catabolic. Have you noticed when you first started working out that you got stronger before you got bigger? From an evolutionary perspective, if you lift something once, your muscles won’t grow. This is because growing muscles and stimulating muscle protein synthesis requires a lot of energy from our cells. However, the repeated stress when regularly lifting weights, will signal the body to eventually adapt and grow.
research-grade anabolic peptide
The master key to Unequivocal, mind-blowing muscle Gains!
Exclusive formula
60% More Anabolic than Leucine
Boosts Muscle Protein Synthesis by 159%
Enhances muscle repair and recovery
research-grade anabolic peptide
The master key to Unequivocal, mind-blowing muscle Gains!
Exclusive formula
Dramatically boosts lower body strength, total strength & lower body reps to failure!
Boosts Muscle Protein Synthesis by 159%
Enhances muscle repair and recovery
introducing
peptide 185™
MuscleTech Researchers, partnered with the cutting-edge formulators behind enfinity® paraxanthine, have harnessed the enzymatic complex responsible for transmitting the body's most powerful anabolic signal in a way that’s never been done before!
Peptide-185™ is a state-of-the-art research grade peptide, composed of two leucine molecules bonded together, creating a unique, patented dipeptide structure known as L-Leucyl-L-Leucine Monohydrate or Dileucine.
how does leucine power muscle Gains?
Muscle protein is in a constant state of turnover, being continuously broken down and resynthesized. Muscle building takes place when the rate of muscle protein synthesis exceeds the rate of muscle protein breakdown. One specific amino acid - L-Leucine is the most powerful and has long been regarded as an anabolic trigger – turning on muscle protein synthesis!
initiates muscle protein synthesis
The mechanism by which leucine initiates muscle protein synthesis is by activating the mammalian target of rapamycin complex 1 (mTORC1) pathway, which is responsible for muscle protein synthesis. Once this anabolic system is activated, leucine will start the production of new muscle protein and begin to produce and repair muscle tissue that has been broken down during hard training.
The Key Regulator
Leucine has been validated by clinical research as the key regulator of the pathway of muscle protein synthesis – playing a critical role in activating muscle anabolism, and without its presence, this activation just doesn’t occur. Thus, the faster leucine gets absorbed and delivered into the muscles, the faster muscle protein synthesis can turn on the pathways of growth and recovery.
Peptide 185™
More Anabolic than Leucine
In the pursuit of getting bigger and stronger faster, researchers have been looking at ways of accelerating the body’s ability to synthesize muscle naturally for decades. The key of course being leucine.
Normally, after you consume protein, digestion breaks the chemical bonds between the amino acids that make up that protein and the result is shorter strings, including free amino acids and dipeptides (dipeptides are short peptides containing only two amino acids). What’s special about dipeptides is that small intestines absorb dipeptides faster than their single-molecule counterparts for maximized amino acid delivery to the muscle.
So, What Would Happen If You Combined Two Leucine Peptides Together?
Researchers did just that when they created L-Leucyl-L-Leucine Monohydrate or Dileucine (DL-185™). Dileucine is a peptide consisting of two leucines chemically bonded to one another that get into the bloodstream intact and can boost protein synthesis even better than regular l-leucine. And we’re not just talking about a “little better” either! In a groundbreaking study, subjects who consumed 2000 mg of DL-185™ demonstrated a massive 159% greater activation of muscle protein synthesis compared to baseline and 60% greater than regular leucine! What is even more interesting is that compared to baseline, leucine did not stimulate muscle protein synthesis, indicating that the intact dileucine is signaling the muscle to resynthesize new muscle proteins!
159% Greater Activation of Muscle Protein Synthesis
In a groundbreaking study, subjects who consumed 2000 mg of DL-185™ found in Peptide 185™ demonstrated a 159% greater activation of muscle protein synthesis compared to baseline and 60% greater than regular leucine.
Reference:
Kevin J.M. Paulussen et al. Dileucine ingestion is more effective than leucine in stimulating muscle protein turnover in young males: a double blind randomized controlled trial. J Appl Physiol 2021, 131:1111–1122
https://journals.physiology.org/doi/full/10.1152/japplphysiol.00295.2021
Anabolic Power that Translates into Huge Gains in Strength!
Activating anabolic muscle protein synthesis is one thing, but how exactly does that translate into real world results in the gym? Researchers set out to determine this in a 10-week resistance training clinical study and the results were mind blowing! Researchers tested lower body strength, total strength, lower body reps to failure, and total reps to failure. Three groups were tested – each day one group took 2,000mg of of DL-185™ found in Peptide 185™, another took only Leucine and a third took a placebo.
Staggering Results after 10 Weeks!
More Total Strength
Subjects taking DL-185™ significantly increased total max strength by 144%, compared to placebo (DL-185™ 154 lbs. vs Placebo 63 lbs.)!
More Lower Body Strength
Subjects also significantly increased their lower body max strength by 189% compared to placebo (DL-185™ 133 lbs. vs Placebo 46 lbs.). If legs are a lagging bodypart for you or you have trouble gaining leg strength - Peptide 185™ should definitely be in your supplement stack!
More Reps Than Leucine
Subjects taking DL-185™ significantly increased leg press repetitions to failure by 220% compared to leucine (DL-185™ 16 extra reps vs leucine 5 extra reps)! Imagine how much you could grow if you could add 16 extra reps to key mass-building exercises like the leg press or even squats?
Rapid Absorption
Peptide 185™ has an ultra-stable and highly bioavailable structure, which allows for a rapid and more efficient absorption of leucine and dileucine via specialized transporters in the gut, directly into the bloodstream.
Why Do I Need Peptide 185™?
Your body can be in one of three states - an anabolic state, in which your muscles grow, a catabolic state, in which your muscles break down, or a neutral state, where your muscle mass neither increases nor decreases.